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Syndromes/Craniofacial Anomalies

279 - Dental Manifestations of Congenital Ewing Sarcoma Treatment: A Case Report

Saturday, May 24, 2025
11:30 AM - 11:45 AM MDT
Has Audio

    Presenting Author(s)

  • Blake Bachner, DDS

    Resident PGY-2
    Case Western Reserve University — UH Rainbow Babies and Children’s Hospital, Cleveland, OH
    Case Western Reserve University — UH Rainbow Babies and Children’s Hospital
    Cleveland, Ohio, United States

    • Co-Author(s)

  • GF

    Gerald Ferretti, DDS

    Pediatric dentistry Chair
    Case Western Reserve University - Rainbow Babies and Children's Hospital
    cleveland, Ohio, United States

  • MF

    Margaret Elaine Ferretti, DMD

    Program Director
    Case Western Reserve University- University Hospitals Rainbow Babies and Children's
    Rainbow Babies and Children's Hospitals, Case Western Reserve University
    Cleveland, Ohio, United States

    • Program Director(s)

  • MF

    Margaret Elaine Ferretti, DMD

    Program Director
    Case Western Reserve University- University Hospitals Rainbow Babies and Children's
    Rainbow Babies and Children's Hospitals, Case Western Reserve University
    Cleveland, Ohio, United States

Abstract: Title: Dental Manifestations of Congenital Ewing Sarcoma: A Case Report

Author: Blake Bachner, Gerald Ferretti, Ying An, Margaret Ferretti

Affiliation: Case Western University- University Hospitals Rainbow Babies and Children’s Hospital

 



Introduction:  Ewing Sarcoma is an aggressive and highly malignant undifferentiated round cell

tumor. Ewing Sarcoma is commonly found in hips, chest wall, and legs of children

between 10-20 years old coinciding with puberty. Cases of congenital Ewing sarcoma in

the head and neck region are extremely rare. Chemotherapy and radiation treatment

early in life can cause devastating effects of dental growth and development including

tooth agenesis, microdontia, crown disturbances, root disturbances, and reduced facial

growth.

 
Case report: This presentation discusses a five-year-old patient seen at University Hospitals

Rainbow Babies and Children Hospital for comprehensive dental care. Patients past

medical history is significant for congenital Ewing Sarcoma of the right masseter region,

chemotherapy (8 days old), head radiation (7 months old), gastrostomy tube, and

previous tracheostomy. Patient was seen for comprehensive oral rehabilitation under

general anesthesia on November 2024. Clinical exam reveals full primary dentition with

grade 1 mobility of primary molars, grade 2 mobility of primary anterior dentition, and

non-restorable caries present on tooth D. Radiographic exam reveals blunted roots of

all primary teeth, agenesis of all permanent teeth with the exception of permanent

incisors and first molars present at the calcification stage, and non-restorable caries on

tooth D. This report outlines immediate treatment and long-term goals considering

social and psychological aspects of a patient lacking nearly all permanent tooth development.

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