370 - Dental Treatment for Patients with Rett Syndrome: A Case Report

Dental Treatment for Patients with Rett Syndrome: A Case Report

Introduction: Rett Syndrome (RS) is a rare, progressive neurodevelopmental disorder, primarily affecting females, caused by gene mutations of MECP2 on the X chromosome impacting neurologic development and cognitive function. RS is characterized by a period of normal development followed by regression and loss of previously acquired behavioral, motor and cognitive skills, muscular hypotonia, epilepsy, scoliosis, and autistic traits.

Case Report:

This case report details the dental rehabilitation completed at Children’s Healthcare of Atlanta for an eight-year-old female diagnosed with Rett Syndrome. Prompt treatment was recommended to mitigate the risk of infection and address suspected pain from a primary tooth fractured due to caries. The full mouth dental rehabilitation completed in an operating room under general anesthesia will be reviewed, along with its rationale, and underlying medical implications associated with this condition.

Identify Supporting Agency and Grant Number: Research supported by Children’s Healthcare of Atlanta